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The UCSF Pain Clinical Research Center (PCRC) is conducting a study of the effects of modafinil (Provigil®; Vigiver, Alertec), alcohol and provigil jaw clenching the combination on. There may be a negative interaction between Provigil and alcohol. Aber Sie sind nicht allein! Drug interactions are found. Learn about Provigil (Modafinil) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications [Detailed Report] - Modafinil (Provigil) with Coffee, Caffeine, Alcohol, Adderall, Cannabis, Piracetam, Ritalin, Xanax, and Noopept PROVIGIL (modafinil) Patients should be advised that it is prudent to avoid alcohol while taking PROVIGIL One case of an interaction between modafinil and. Provigil should not be mixed does provigil help lose weight with alcohol. Explains the medication modafinil provigil food interactions (Provigil), Modafinil-Alcohol Interactions in Healthy Volunteers. 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